- August 20, 2025
- Posted by: Josh Knoll
- Category: Specialty Pharmacy

Do you know that more than half of the specialty pharmacies’ operational teams struggle with the fundamentals of billing operations? If you’re stumbling with the same, worry no more, as you’re not alone. A survey shows that more than 50% of patients feel confused about drug coverage. Today, more than 43% of specialty pharmacy centers end up losing tons of money due to improper billing. So, what’s the solution to this problem? The solution is to outsource a specialty pharmacy billing company that can streamline the billing process. There are two main ways in which specialty drugs are covered. These are buy-and-bill and specialty pharmacy. And it depends a lot on how care is given. In buy-and-bill, doctors buy the drugs first. They store them and give them to patients. Later, they bill the insurance. This gives doctors more control. But if insurance denies the claim, the clinic loses money. In contrast, specialty pharmacies send drugs directly to patients or clinics. The pharmacy manages approvals, billing, and payment. This lowers the risk for doctors. But treatment may be delayed because of approvals and shipping. Also, it is important to know that it has various types of billing models. Related Reading: How Do You Get your Specialty Pharmacy Billing Fixed? Specialty drugs don’t move like normal prescriptions. They need special billing and delivery systems. Also, bagging here works differently. In this model, the specialty pharmacy ships the drug. It may go to the provider’s office (white bagging) or straight to the patient (brown bagging). Here, providers don’t face financial risk. But treatment can be delayed due to shipping, storage, or insurance approvals. Given the confusion, it’s crucial to understand how they operate in specialty drug billing. Buy-and-bill is common in specialty care. It is mostly used for drugs given in a clinic or hospital. Examples are cancer infusions, biologics, and high-cost injections. Here is how it works. The doctor or clinic buys the drug from a supplier. They keep it in stock. When the patient comes in, the clinic gives the drug. After that, the clinic sends a bill for the drug and the service. This model gives doctors control. They can keep the drug safe. They can also start treatment right away. For patients, this means fewer delays. But there are risks. These drugs are very costly. Clinics must pay first and wait weeks to get money back. If the insurance company denies the claim, the clinic may lose money. Still, buy-and-bill is used a lot. It covers a big share of specialty drug spending. Even with challenges, it remains an important way for patients to get treatment. But if you face an issue in choosing the right pharmacy model, you may consider outsourcing to a specialty pharmacy billing company to take care of this process. When buy-and-bill is not possible, practices turn to bagging models. White bagging ships drugs from a specialty pharmacy to the provider. It lowers cost risk but adds storage steps. Brown bagging sends drugs to patients, who bring them to the clinic. This cuts provider costs but raises safety issues. Clear bagging uses the health system’s own specialty pharmacy. It offers safer handling and fewer delays. Practices choose bagging when drug costs are too high or payers mandate pharmacy benefits. Clear bagging offers the most control. Brown bagging is the riskiest. Prescription billing and medical billing may sound the same. But they follow very different paths. Prescription billing happens at retail or specialty pharmacies. The claim is sent through a pharmacy benefit manager (PBM). The patient usually pays a copay at the counter. Insurance covers the rest. This system is quick and made for fast approvals. At the same time, medical billing happens inside clinics or hospitals. The drug is linked to a medical service, such as an infusion or injection. The provider gives the treatment first. After that, the claim goes to the medical benefit side of insurance. Payments take longer and need more paperwork. The biggest difference is who handles the claim and how the drug is paid for. Prescription billing is pharmacy-driven. Medical billing is provider-driven. This gap changes cost, speed, and patient experience. The outsourced specialty pharmacy billing company has the knowledge of which billing process to use in which situation. Ever wondered why one drug is easy to get while another takes weeks of back-and-forth? The answer lies in how drugs move through insurance benefits and formularies. Here’s the flow: Medical benefit = heavier admin load, higher risk of delays and denials. Thus, to overcome these issues, you may need the help of a reputable specialty pharmacy billing company. There are multiple stakeholders in specialty pharmacy. Each has different responsibilities and tasks, which are described below: Payers are insurance companies, Medicare, Medicaid, and PBMs. They decide which drugs are covered. They check claims, approve medicines, and see how patients take their drugs. They also make lists of covered medicines called formularies and offer help programs for patients. Distributors move drugs from makers to pharmacies. They handle orders and storage. They keep track of stock to avoid shortages. Some also help patients pay for expensive medicines. PBMs manage drug benefits for health plans and employers. They set prices, create formularies, process claims, and suggest cheaper generics. Some run specialty pharmacies. Specialty pharmacies provide medicines for deadly conditions. These include cancer, MS, or HIV. By managing drugs and billing, they reduce risks for doctors. Healthcare providers prescribe and give the drugs. They send claims for the drug and the service. Providers also counsel patients and may collect copays. It is no secret that the high-cost drugs of specialty clinics bring many hurdles for clinics and hospitals, and so there are specialty pharmacy billing companies that help: Outsourcing to a reputable specialty pharmacy billing company helps clinics manage money better. Billing experts handle claims that are often complex and time-consuming. They know insurance rules, so errors go down and approvals go up. This leads to faster payments and fewer rejected claims. Clinics can save staff hours and focus more on patient care. Related Reading: Why Should You Outsource Specialty Pharmacy Billing Services Do you face billing issues, late payments, or high costs? SunKnowledge is there to help you. SunKnowledge is one of the best RCM companies in the US. We not only help the providers, but we also have expertise working with the payers. There are several areas in which we can help, such as: We can reduce your operational costs by 80%. Moreover, we work with 99.9% accuracy to make sure no claim denial occurs. Furthermore, we have proven expertise in working with major specialty pharmacies, and we have dedicated resources working in different time zones. Apart from that, we don’t have any binding contracts or restrictive clauses. What else? We provide dedicated account managers at no extra cost. So, if you want to streamline your billing process, contact SunKnowledge today and make your pharmacy billing stress-free. Specialty drugs are billed under either the medical benefit or the pharmacy benefit, based on the drug and insurance plan. For medical billing, the provider files a claim like any other procedure. Medical billing is used for hospital visits, doctor services, and procedures. Pharmacy billing is used for filling prescriptions. Medical billing uses CPT and HCPCS codes. Pharmacy billing uses NDC codes. Pharmacies use NDC codes (National Drug Codes) for most medications. CPT codes may also apply when a drug is given with a service. These codes help insurance companies identify the drug and pay correctly. Pharmacies send claims to insurance companies or PBMs after filling a prescription. The insurer checks if the patient has coverage. If approved, the insurer pays the pharmacy for the drug cost minus any copay from the patient. Payments are usually electronic and done quickly. Understanding The Complex Area Of The Buy-and-Bill Landscape Of Specialty Pharmacy
The Various Types Of Bagging Models in Specialty Pharmacy Centers
Detailed Functions of Buy-and-Bill in the Specialty Pharmacy Landscape
Alternatives to Buy-and-Bill: When to Choose White/Clear/Brown Bagging
Prescription Billing vs Medical Billing: Core Differences
Drug Coverage For Specialty Pharmacy: How Drugs Move Through Benefits and Formularies
Detailed analysis of Medical Benefit vs Pharmacy Benefit: Practical Comparison
Pharmacy Benefit Medical Benefit Why it matters Think about regular prescriptions from your local pharmacy. This covers drugs given in clinics or hospitals, like infusions or injections. Pharmacy benefit = faster processing, more transparency in patient out-of-pocket costs. The pharmacy gives the medicine, bills the insurance online, and the patient pays any copay immediately. Billing is done through medical claims using CPT or J-codes, not through the pharmacy checkout system. Specialty pharmacies handle harder-to-manage drugs. Payment may come weeks later because claims go through manual review. They take care of approvals, refills, and help patients use the medicine correctly. Stakeholder Roles in Specialty Pharmacy: Who Does What
Challenges Practices Face
Benefits of Outsourcing to a Specialty Pharmacy Billing Company
SunKnowledge: An Expert Partner for Specialty Pharmacy Billing
FAQs
How are specialty medications billed?
What is the difference between medical billing and pharmacy billing?
What are the most common billing codes used in a pharmacy?
How do pharmacies get paid by insurance plans?
